5545757
Tocris Bioscience™ CP 376395 hydrochloride
Potent and selective CRF1 antagonist; binds at an allosteric site
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
CP 376395 hydrochloride
Molecular Weight (g/mol)
362.94
Inhibitors
CP 376395 hydrochloride
Related Products
Description
- Potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000 nM for CRF1 and CRF2 receptors respectively)
- Attenuates CRF-induced activation of the HPA axis in vivo following i.v
- administration
- Orally active.