5545749
Tocris Bioscience™ CITCO
Selective CAR agonist
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
CITCO
Molecular Weight (g/mol)
436.74
Inhibitors
CITCO
Related Products
Description
- Constitutive androstane receptor (CAR) agonist (EC50 = 49 nM)
- Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ERα, ERβ, PPAR, RAR, FXR, VDR and THR
- Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro .