5545837
Tocris Bioscience™ IWP L6
Potent PORCN inhibitor
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
IWP L6
Molecular Weight (g/mol)
472.58
Inhibitors
IWP L6
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Description
- Potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM)
- Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys.