5545872
Tocris Bioscience™ LY 2389575 hydrochloride
Selective negative allosteric modulator of mGlu3
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
LY 2389575 hydrochloride
Molecular Weight (g/mol)
438.58
Inhibitors
LY 2389575 hydrochloride
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Description
- Selective negative allosteric modulator of mGlu3 (IC50 = 190 nM)
- Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors
- Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.