5545947
Tocris Bioscience™ OXF BD 02
Selective BRD4(1) inhibitor
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
OXF BD 02
Molecular Weight (g/mol)
295.33
Inhibitors
OXF BD 02
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Description
- Selective inhibitor of the first bromodomain of BRD4 (BRD4(1)) (IC50 = 382 nM)
- Exhibits 2-3-fold selectivity for BRD4(1) over the CBP bromodomain and has little affinity for a range of other bromodomains
- Reduces viability of lung adenocarcinoma cell lines and attenuates proliferation of MV-4-11 leukemia cells
- Cell permeable.