5545982
Tocris Bioscience™ Pyridostatin pentahydrochloride
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
Manufacturer: Fischer Scientific
CAS Number: 1781882-65-2
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CAS
1781882-65-2
Product Type
Pyridostatin pentahydrochloride
Inhibitors
Pyridostatin pentahydrochloride
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Medchem Express / Pyridostatin (hydrochloride) / 5mg / 446265082 / HY-15176A / / 1781882-65-2 / MFCD28133372 / 778.940 / C31H37Cl5N8O5 | -- | ₹ 13,349.93 | |
| | Tocris Bioscience™ Pyridostatin pentahydrochloride | -- | ₹ 29,304.30 | |
| | Tocris Bioscience™ Pyridostatin pentahydrochloride | -- | -- | |
| | 1781882-65-2 | Pyridostatin hydrochloride | -- | ₹ 12,063.96 - ₹ 78,629.64 |
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Description
- Binds and stabilizes G-quadruplexes, inducing DNA damage and cell cycle arrest (Kd = 490 nM); targets the proto-oncogene Src, reducing Src protein abundance and Src-dependent motility in human breast cancer cells
- Also targets telomeric G-quadruplexes, inducing telomerase dysfunction
- Activates the DNA-dependent protein kinase catalytic sunbunit (DNA-PKcs).