51-211-0
Tocris Bioscience™ 3PO
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 51-211-0-Each-of-1 | In Stock | ₹ 12,132.41 |
51-211-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 12,132.41
GST (18%): ₹ 2,183.834
Total Price: ₹ 14,316.244
Purity
>99%
Product Type
3PO
Inhibitors
3PO
Quantity
10 mg
Molecular Weight (g/mol)
210.23
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Description
- Originally reported to inhibit PFKFB3 (IC50 = 25 μM)
- More recent reports failed to demonstrate activity in a PFKFB3 kinase assay
- Reduces glycolytic flux and suppresses glucose uptake
- Inhibits endothelial cell proliferation and causes G2/M cell cycle arrest in vitro
- Attenuates vessel sprouting and tumor growth in vivo
- Amplifies the antiangiogenic effect of VEGFR blockade.