5546128
Tocris Bioscience™ AC 5216
Selective TSPO ligand
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
AC 5216
Molecular Weight (g/mol)
401.46
Inhibitors
AC 5216
Related Products
Description
- Ligand of translocator protein (TSPO, peripheral benzodiazepine receptor)
- Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively)
- Displays no noticeable binding to a number of other receptors, transporters or ion channels
- Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.