5546193
Tocris Bioscience™ T 5601640
Selective LIMK2 inhibitor; antitumor
Manufacturer: Fischer Scientific
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Purity
>99%
Product Type
T 5601640
Molecular Weight (g/mol)
389.33
Inhibitors
T 5601640
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Description
- Selective LIM kinase 2 (LIMK2) inhibitor; inhibits cofilin phosphorylation in cells that overexpress LIMK2 but not LIMK1
- Attenuates the growth of several cancer cell lines
- Reduces phospho-cofilin levels and Panc-1 tumor size in a mouse xenograft model.