PI35603

Thermo Scientific™ Pierce™ Iodoacetic Acid

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Pack of 1 PI35603-Pack-of-1 In Stock ₹ 10,489.66

PI35603 - Pack of 1

₹ 10,489.66

In Stock

Quantity

1

Base Price: ₹ 10,489.66

GST (18%): ₹ 1,888.139

Total Price: ₹ 12,377.799

Chemical Reactivity

Thiol

Content And Storage

Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, between the following temperatures: 2 to 8°C.

Label Type

Blocking Groups

Spacer

Short (<10 Å)

Quantity

500 mg

Product Type

Iodoacetic Acid

Description

Iodoacetic Acid

Label or Dye

Unreactive Group

Product Line

Pierce™

Form

Powder

Solubility

Water

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Description

  • Description Get rapid carboxymethylation of reduced cysteine residues with Thermo Scientific™ Pierce™ Iodoacetic Acid and Iodoacetamide
  • Iodoacetic Acid (IAA) can react with several protein functional groups but is typically used for specific S-carboxymethylation of sulfhydryls (reduced cysteines)
  • Iodoacetic acid reacts with sulfhydryls on cysteines, imidazolyl side chain nitrogens of histidines, the thioether of methionine and the primary amine group of lysines.The rate of reaction and specificity is dependent on the ionization level, which can be manipulated by the pH of the reaction condition
  • Highlights: React at slightly alkaline pH for specific S-carboxymethylation of free sulfhydryls React at low pH for specific carboxymethylation of methionines React at high pH to favor carboxymethylation of histidines and lysines Methylate reduced cysteine peptide fragments in protease digests for mass spectrometry