50-049-80001
MilliporeSigma™ Calbiochem™ HIF Inhibitor V
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-049-80001-Each-of-1 | In Stock | ₹ 20,906.59 |
50-049-80001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 20,906.59
GST (18%): ₹ 3,763.186
Total Price: ₹ 24,669.776
Color
White
Molecular Formula
C32H38N2O5
Solubility
DMSO
Form
Powder
Description
99% by HPLC
Formula Weight
530.7g/mol
Content And Storage
Protect from light
Quantity
10 mg
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Description
- A cell-permeable phenoxyacrylamido compound that inhibits hypoxia-induced cellular HIF-1α accumulation in a manner similar to LW6 (Cat
- No
- 400083) by upregulating Hippel-Lindau tumor suppressor gene product pVHL, but with much higher potency (IC 50 = 120nM vs 2.44μM, respectively, against hypoxia-induced HRE reporter activity in HCT116 cells)
- Shown to suppress HIF-1 target genes expression in HCT116 cultures and inhibit HUVEC tubule formation (effective conc
- ≥2μM) under hypoxia conditions
- Please note that the molecular weight for this compound is batch-specific due to variable water content
- Please refer to the vial label or the certificate of analysis for the batch-specific molecular weight
- The molecular weight provided represents the baseline molecular weight without water.