50-527-60001

MilliporeSigma™ Calbiochem™ HSP70 Activator II, YM-08

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 50-527-60001-Each-of-1 In Stock ₹ 26,049.60

50-527-60001 - Each of 1

₹ 26,049.60

In Stock

Quantity

1

Base Price: ₹ 26,049.60

GST (18%): ₹ 4,688.928

Total Price: ₹ 30,738.528

Color

Orange

Target Proteins

HSP70

Solubility

DMSO

Form

Solid

Description

99% by HPLC

Molecular Formula

C19H17N3OS2

Content And Storage

Protect from light

Quantity

10 mg

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Description

  • A cell-permeable, neutrally charged, pyridinium-to-pyridine substituted YM-01 (Cat
  • No
  • 500615) and MKT-077 structural analog that exhibits higher HSP70-binding affinity, but reduced tau degradation-promoting potency in cultures (% degradation of p-tau/total tau = 42/64, 88/89, and 81/80 in HeLaC3 with 30μM YM-08, MKT-077, or YM-01, respectively) and weaker anti-cancer activity (IC 50 against MDA-MB-231/MCF10A/MCF7 inμM = 1.4/3.0/2,2/MKT-077, 2.0/3.3/5.2/YM-01, and 8.5/7.8/10.5/YM-08 in 72 h).