7091166

Mouse IgG2a kappa Isotype Control (eBM2a), eFluor™ 450, eBioscience™, Invitrogen™

Mouse Isotype Control

Manufacturer: Fischer Scientific

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Antigen

Mouse IgG2a kappa

Concentration

0.2 mg/mL

Conjugate

eFluor 450

Host Species

Mouse

Target Species

Not Applicable

Gene Alias

IgG2; Immunoglobulin G; Immunoglobulin G2; ImmunoglobulinG; ImmunoglobulinG2

Primary or Secondary

Isotype Control (Primary)

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

eBM2a

Applications

Control, Flow Cytometry

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Isotype

IgG2a κ

Purification Method

Affinity chromatography

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Description

  • Description: This is a monoclonal mouse IgG2a, kappa antibody
  • It is used as an isotype control for mouse IgG2a antibodies
  • Applications Reported: Mouse IgG2a K Isotype Control eFluor® 450 has been reported for use in flow cytometric analysis
  • Applications Tested: eFluor® 450 Mouse IgG2a, K Isotype Control has been tested by flow cytometric analysis of normal human peripheral blood cells
  • Use isotype control at the same concentration as experimental antibody
  • Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • Mouse IgG2a is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen
  • It is the second most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response
  • Mouse IgG2a is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity
  • It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation
  • Mouse IgG2a is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry
  • It is also used in therapeutic applications, such as immunotherapy and vaccine development.