K1712

Thermo Scientific™ GeneBLAzer™ 5TH1A-Gα15-NFAT-blaCHO-K1 Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1712-Each-of-1 In Stock ₹ 9,05,224.80

K1712 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Accession Number

NM_000524

Cell State

Dividing Cells

Detection Method

Fluorescence

Gene Symbol

5HT1A

Product Line

GeneBLAzer™

Reporter Gene

BLA (Beta-Lactamase)

Cell Line

CHO-K1

Druggable Target

GPCR

Assay Entry

Cell-based beta lactamase reporter gene

Content And Storage

LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ 5HT1A Gα15-NFAT-blaCHO-K1 cells• GeneBLAzer™ 5HT1A Gα15-NFAT-blaCHO-K1 Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ 5HT1A Gα15 CHO-K1 DA cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.

For Use With (Application)

FRET

Population Status

Single Cell Clone Origin

Quantity

2 x 106Cells

Target Entry

5HT1A, HTR1A

System Type

GeneBLAzer™

Related Products

Img

Thermo Scientific™

K1735

--

Img

Thermo Scientific™

K1716

--

Img

Thermo Scientific™

K1715

--

Img

Thermo Scientific™

K1737

--

Img

Thermo Scientific™

K1748

--

Img

Thermo Scientific™

K1532

--

Img

Thermo Scientific™

K1719

--

Img

Thermo Scientific™

K1529

--

Description

  • GeneBLAzer™ 5HT1A Gα15-NFAT- bla CHO-K1 cells contain the human 5-HT Receptor 1A (5HT1A) stably integrated into the GeneBLAzer™ Gα15-NFAT- bla CHO-K1 cell line
  • GeneBLAzer™ Gα15-NFAT- bla CHO-K1 cells (Cat
  • no
  • K1537) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element and the Promiscuous G protein, Gα15
  • The GeneBLAzer™ 5HT1A Gα15-NFAT- bla CHO-K1 cells are functionally validated for Z' and EC 50 concentrations of 5-CT
  • In addition, GeneBLAzer™ 5HT1A Gα15-NFAT- bla CHO-K1 cells have been tested for assay performance under variable conditions
  • These data are found in the Validation & Assay Performance Summary
  • Agonists and antagonists of the 5HT receptors are in various stages of clinical trials for the treatment of neurological disorders like anxiety, insomnia, and depression
  • For Academic pricing please login or contact us at discoverysciences@invitrogen.com.