P6282

Poly-ʟ-Lysine Hydrobromide

synthetic, mol wt 70,000-150,000, powder, γ-irradiated, suitable for cell culture, BioXtra

Manufacturer: Sigma Aldrich

CAS Number: 25988-63-0

Synonym(S): PLL HBr

Select a Size

Pack Size SKU Availability Price
5 MG P6282-5-MG In Stock ₹ 9,834.60

P6282 - 5 MG

₹ 9,834.60

In Stock

Quantity

1

Base Price: ₹ 9,834.60

GST (18%): ₹ 1,770.228

Total Price: ₹ 11,604.828

product name

Poly-L-lysine hydrobromide, mol wt 70,000-150,000, lyophilized powder, γ-irradiated, BioXtra, suitable for cell culture

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

form

lyophilized powder

mol wt

70,000-150,000

packaging

pkg of 5 mg

technique(s)

cell culture | mammalian: suitable

surface coverage

4 μg/cm2

Other Options

Image Product Name Manufacturer Price Range
Electron Microscopy Sciences Poly-L-Lysine 0.1% Solution, 25988-63-0, 10ml
-- ₹ 3,422.40
Sigma Aldrich Fine Chemicals Biosciences Poly-L-lysine Solution | 25988-63-0 | MFCD00165424 | 500ml
-- ₹ 55,340.21
Sigma Aldrich Fine Chemicals Biosciences Poly-L-lysine solution | 25988-63-0 | MFCD00165424 | 100 mL
-- ₹ 16,455.75
Supply Solutions Poly-L-lysine solution, 25988-63-0, MFCD00165424, 50mL
-- ₹ 12,423.31
Poly-L-lysine hydrobromide
-- ₹ 6,490.00 - ₹ 1,02,641.70
Poly-L-lysine hydrobromide
-- ₹ 7,040.00 - ₹ 77,011.80
Poly-L-lysine hydrobromide
-- ₹ 7,004.10 - ₹ 68,609.10
Poly-L-lysine hydrobromide
-- ₹ 4,972.80 - ₹ 67,743.30
Poly-L-lysine hydrobromide
-- ₹ 7,703.40 - ₹ 72,405.30
Poly-L-lysine hydrobromide
-- ₹ 6,216.00 - ₹ 69,408.30

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Description

  • General description: Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O containing moieties.
  • Application: Poly-L-lysine hydrobromide has been used to precoat glass bottom dishes used for in vitro cell culture.[1][2][3]
  • Biochem/physiol Actions: Poly-L-lysine serves as a pre-coating substance to ensure better attachment of cells to culture surfaces.[4] Research shows that plates coated with poly-L-lysine (PLL) demonstrated an accelerated cell growth rate.[5] Culturing mesenchymal stem cells (MSCs) on PLL-coated substrates has been found to safeguard the stemness properties of these cells and inhibit senescence. PLL-coated plates have demonstrated enhanced MSC growth and up-regulated the expression of genes associated with cell adhesion, differentiation, proliferation, and signaling. Moreover, porous PLL-coated surfaces have shown improvements in cell proliferation and the osteogenic differentiation of MSCs.[6]
  • Components: Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O containing moieties.
  • Caution: Sterile solutions are stable for up to 2 years when stored at 2-8°C. It should be stored desiccated at -20°C.
  • Analysis Note: Molecular weight based on viscosity. Also assayed by MALLS.
  • Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves