P6532

Prostaglandin E2

γ-irradiated, powder, BioXtra, suitable for cell culture

Manufacturer: Sigma Aldrich

CAS Number: 363-24-6

Synonym(S): (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid, Dinoprostone, PGE2

Select a Size

Pack Size SKU Availability Price
1 MG P6532-1-MG In Stock ₹ 36,924.08

P6532 - 1 MG

₹ 36,924.08

In Stock

Quantity

1

Base Price: ₹ 36,924.08

GST (18%): ₹ 6,646.334

Total Price: ₹ 43,570.414

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

form

powder

potency

0.25-100 ng/mL

technique(s)

cell culture | mammalian: suitable

solubility

ethanol: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

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Description

  • Application: For use in cell culture applications for the study of prostaglandin regulated cell signaling and gene regulation.
  • Biochem/physiol Actions: Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
  • Physical form: powder -20 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H360FD

Precautionary Statements

P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves