S8751

Sulfaguanidine

Manufacturer: Sigma Aldrich

CAS Number: 57-67-0

Synonym(S): 4-Amino-N-(aminoiminomethyl)benzenesulfonamide, 4-Amino-N-guanylbenzenesulfonamide

Select a Size

Pack Size SKU Availability Price
25 G S8751-25-G In Stock ₹ 2,186.65

S8751 - 25 G

₹ 2,186.65

In Stock

Quantity

1

Base Price: ₹ 2,186.65

GST (18%): ₹ 393.597

Total Price: ₹ 2,580.247

biological source

synthetic (Organic)

Quality Level

200

form

powder

color

white to off-white

solubility

1 M HCl: soluble 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteriaGram-positive bacteria

Mode of action

DNA synthesis | interferesenzyme | inhibits

SMILES string

NC(=N)NS(=O)(=O)c1ccc(N)cc1

InChI

1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

InChI key

BRBKOPJOKNSWSG-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
VETRANAL™ Sulfaguanidine, MilliporeSigma™ Supelco™
-- ₹ 9,069.36
eMolecules​ Ambeed / 4-Amino-N-carbamimidoylbenzenesulfonamide / 25g / 506390111 / A293011 / / 57-67-0 / MFCD00038136 / 214.240 / C7H10N4O2S
-- ₹ 2,240.82
Sulfaguanidine
-- ₹ 7,718.23
Sulfaguanidine
-- ₹ 2,186.65
Sulfaguanidine
-- ₹ 13,176.24 - ₹ 21,817.80
57-67-0 | Sulfaguanidine
-- ₹ 855.60 - ₹ 5,646.96

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Description

  • General description: Chemical structure: sulfonamide
  • Application: Sulfaguanidine is used to block the synthesis of folic acid. It is used to study its effect on microsporidial growth and host cell viability[1].
  • Biochem/physiol Actions: Sulfaguanidine is a sulfonamide antibiotic. Sulfonamides block the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfonamides are competitive inhibitors of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid[2]. Sulfaguanidine is a dihydrofolate reductase (DHFR) inhibitor. Sulfonamides are active against Gram positive bacteria and Gram negative bacteria. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves