SBR00017

Puromycin aminonucleoside Ready Made Solution

10 mg/mL in water

Manufacturer: Sigma Aldrich

CAS Number: 58-60-6

Synonym(S): 3′-Amino-3′-deoxy-N6,N6-dimethyladenosine

Select a Size

Pack Size SKU Availability Price
1 ML SBR00017-1-ML In Stock ₹ 16,486.48

SBR00017 - 1 ML

₹ 16,486.48

In Stock

Quantity

1

Base Price: ₹ 16,486.48

GST (18%): ₹ 2,967.566

Total Price: ₹ 19,454.046

Assay

≥98%

Quality Level

200

form

liquid

concentration

10 mg/mL in water

antibiotic activity spectrum

Gram-positive bacterianeoplasticsparasites

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

N[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C)C)=NC=N3)O[C@@H]1CO

InChI

1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3

InChI key

RYSMHWILUNYBFW-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
Puromycin aminonucleoside
-- ₹ 36,447.78 - ₹ 2,60,720.13
Puromycin aminonucleoside
-- ₹ 36,447.78 - ₹ 2,60,720.13
Puromycin aminonucleoside Ready Made Solution
-- ₹ 16,486.48
Puromycin aminonucleoside
-- ₹ 16,598.64 - ₹ 82,308.72
58-60-6 | PUROMYCIN AMINONUCLEOSIDE
-- ₹ 4,791.36 - ₹ 32,085.00

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Description

  • Biochem/physiol Actions: Puromycin aminonucleoside is an aminonucleoside derivative of the known antibiotic puromycin. Puromycin aminonucleoside has been used in nephrology research, studying focal and segmental glomerulosclerosis, and in the induction of nephrosis in rats.[1][2][3] Rats with puromycin aminonucleoside-induced nephrotic syndrome were used to study the excretion of sodium and NOx metabolites.[4]Puromycin aminonucleoside has also been used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeability.[5] A puromycin aminonucleoside nephrosis model of rat glomerular disease was also used to study the role of the neuron-specific ubiquitin C-terminal hydrolase protein gene product 9.5 (PGP 9.5).[6]
  • Preparation Note: Puromycin aminonucleoside solution is provided at 10 mg/mL in water and could be further diluted in aqueous buffers to a working concentration of 10 μg/mL (1:1000).

SAFETY INFORMATION

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable