D8893

Dexamethasone

powder, γ-irradiated, BioXtra, suitable for cell culture, ≥80% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 50-02-2

Synonym(S): (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F

Select a Size

Pack Size SKU Availability Price
1 MG D8893-1-MG In Stock ₹ 7,739.88

D8893 - 1 MG

₹ 7,739.88

In Stock

Quantity

1

Base Price: ₹ 7,739.88

GST (18%): ₹ 1,393.178

Total Price: ₹ 9,133.058

biological source

synthetic (organic)

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

Assay

≥80% (HPLC)

form

powder

potency

4-500 ng/mL

technique(s)

cell culture | mammalian: suitable

mp

262-264 °C (lit.)

solubility

ethanol: 1 mL/vial, clear

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Description

  • Application: Dexamethasone has been used as a component of osteogenic differentiation medium.[1][2][3] It has also been used to study apoptosis, cell signaling pathways and gene expression.
  • Biochem/physiol Actions: Dexamethasone has immunosuppressant and antiemetic properties. It is used to treat postoperative nausea and vomiting (PONV) and chemotherapy-induced nausea and vomiting (CINV).[4] Dexamethasone plays an important role in cardiac transplant, sepsis, cancer and other pathologic disorders. It elevates the level of heat shock proteins.[5] It is an anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression.
  • Physical form: powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
  • Reconstitution: To prepare 20 μg/ml stock solution: add 1 ml absolute ethanol; gently swirl to dissolve; add 49 ml sterile medium while mixing.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H360FD

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves