42-029-7100UG

MilliporeSigma™ Calbiochem™ InSolution™ K-252a, Nocardiopsis sp.

Manufacturer: MilliporeSigma™

CAS Number: 97161-97-2

Select a Size

Pack Size SKU Availability Price
Each of 1 42-029-7100UG-Each-of-1 In Stock ₹ 22,793.18

42-029-7100UG - Each of 1

₹ 22,793.18

In Stock

Quantity

1

Base Price: ₹ 22,793.18

GST (18%): ₹ 4,102.772

Total Price: ₹ 26,895.952

Formulation

A 1 mM (100μg/214μl) solution of K-252a in DMSO.

Target Proteins

CaM kinase II

Molecular Formula

C27H21N3O5

Content And Storage

Hygroscopic, Protect from light

Quantity

100 μg

Description

95% by HPLC

CAS

97161-97-2

Formula Weight

467.5g/mol

Form

Liquid

Other Options

Image Product Name Manufacturer Price Range
97161-97-2 | K252a
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Description

  • A cell-permeable protein kinase inhibitor that inhibits CaM kinase II (K i = 1.8nM), myosin light chain kinase (K i = 17nM), protein kinase A (K i = 18nM), protein kinase C (K i = 25nM), and protein kinase G (K i = 20nM)
  • Also acts as a potent inhibitor (IC 50 = 3nM) of the tyrosine protein kinase activity of the NGF receptor gp 140trk, the product of the trk protooncogene
  • Also inhibits the kinase activity of its transforming alleles, the trk oncogenes, and of the related neurotrophin receptors gp 145trkB and gp 145trkC
  • Induces apoptosis and cell cycle arrest by inhibiting Cdc2 and Cdc25c.