56-632-11MG
MilliporeSigma™ Calbiochem™ InSolution™ Sirtinol
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-632-11MG-Each-of-1 | In Stock | ₹ 10,540.14 |
56-632-11MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 10,540.14
GST (18%): ₹ 1,897.225
Total Price: ₹ 12,437.365
Formulation
A 10 mM (1mg/254μl) solution of Sirtinol in DMSO.
Target Proteins
ySir2
Formula Weight
394.5g/mol
Form
Liquid
Description
97% by HPLC
Molecular Formula
C26H22N2O2
Content And Storage
Hygroscopic, Protect from light
Quantity
1 mg
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Description
- A cell-permeable 2-hydroxy-1-napthaldehyde derivative that acts as a specific and a direct inhibitor of sirtuin class of histone deacetylase (HDAC) activity
- Does not affect human HDAC1
- Reported to block Sir2p transcriptional silencing activity in vivo (IC 50 = 25μM) and NAD-dependent HDAC activity in purified recombinant yeast Sir2p and human SIRT2 in vitro (IC 50 = 68μM and 38μM, respectively).