57-263-6500UG

MilliporeSigma™ Calbiochem™ InSolution™ SU6656

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 57-263-6500UG-Each-of-1 In Stock ₹ 14,736.00

57-263-6500UG - Each of 1

₹ 14,736.00

In Stock

Quantity

1

Base Price: ₹ 14,736.00

GST (18%): ₹ 2,652.48

Total Price: ₹ 17,388.48

Formulation

A 10 mM (500μg/135μl) solution of SU6656 in DMSO.

Target Proteins

Src

Formula Weight

371.5g/mol

Form

Liquid

Description

95% by HPLC

Molecular Formula

C19H21N3O3S

Content And Storage

Hygroscopic, Protect from light

Quantity

500 μg

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Description

  • A potent inhibitor of Src-family protein tyrosine kinases
  • Inhibits Src (IC 50 = 280nM) as well as closely related kinases Fyn (IC 50 = 170nM), Yes (IC 50 = 20nM) and Lyn (IC 50 = 130nM)
  • The inhibition is competitive with respect to ATP
  • Has only a trivial effect on Lck (IC 50 = 6.88μM)
  • Does not affect the activity of PDGF-β receptor kinase (IC 50 >10μM) and IGF-1 receptor kinase (IC 50 gt;20μM).