56-786-010MG
MilliporeSigma™ Calbiochem™ SRT1720
Manufacturer: MilliporeSigma™
CAS Number: 925434-55-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 56-786-010MG-Each-of-1 | In Stock | ₹ 22,793.18 |
56-786-010MG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 22,793.18
GST (18%): ₹ 4,102.772
Total Price: ₹ 26,895.952
Color
Yellow
CAS
925434-55-5
Formula Weight
469.6g/mol
Content And Storage
Protect from light
Quantity
10 mg
Description
97% by HPLC
Molecular Formula
C25H23N7OS
Solubility
DMSO
Form
Solid
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ SRT 1720 | -- | -- | |
| | Tocris Bioscience™ SRT 1720 | -- | ₹ 17,753.70 | |
| | Tocris Bioscience™ SRT 1720 | -- | ₹ 74,693.88 | |
| | eMolecules Medchem Express / SRT 1720 / 10mg / 437899016 / HY-10532 / / 925434-55-5 / MFCD14584468 / 469.570 / C25H23N7OS | -- | ₹ 11,334.99 | |
| | Medchemexpress LLC HY-10532 10mg Medchemexpress, SRT 1720 CAS:925434-55-5 Purity:>98% | -- | ₹ 8,085.42 | |
| | 925434-55-5 | Srt1720 | -- | ₹ 5,304.72 - ₹ 78,800.76 |
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Description
- A cell-permeable quinolinecarboxamide compound that is shown to inhibit the mitochondrial SIRT3 in a substrate AceCS2-competitive ( K i = 0.56μM; K m = 2.44μM), but NAD + -uncompetitive ( K i = 0.34μM; K m = 280μM), manner
- Also reported to decrease cellular p53 Lys382 acetylation (Effective conc
- = 10μM in U2OS and MEF cultures) and inhibit p300 HAT activity (IC 50 = 9μM) in vitro , as well as offer therapeutic benefits in several murine and rodent type 2 diabetes models (100mg/kg/dayl p.o.) in vivo
- Whether and how SRT1720 activates SIRT1 activity remains uncertain
- Also available as a 25mm solution in DMSO (Cat
- No
- 530748).