50-471-20001
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor VI, ICG-001
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-471-20001-Each-of-1 | In Stock | ₹ 26,049.60 |
50-471-20001 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,049.60
GST (18%): ₹ 4,688.928
Total Price: ₹ 30,738.528
Color
Off-white
Target Proteins
CREB-binding protein
Solubility
DMSO
Form
Powder
Description
99% by HPLC
Molecular Formula
C33H32N4O4
Content And Storage
Protect from light
Quantity
10 mg
Related Products
Description
- A cell-permeable pyrazinopyrimidinecarboxamide that competes against β-catenin for CBP (CREB-binding protein) binding and selectively prevents CBP- but not p300-, dependent TCF/β-catenin transcriptional regulations both in cultures in vitro (5 to 25μM) and in mice in vivo (5mg/kg/day via osmotic pump infusion), while not affecting CBP-dependent transcriptional activities mediated by the AP-1 or CRE complex
- Shown to reactivate p300//TCF/β-catenin-mediated neuronal differentiation upon NGF stimulation in PS-1 L286V mutant-expressing PC-12 cultures and be efficacious in alleviating bleomycin- (0,08 units/50μL/mouse; administered intranasally; Cat
- No
- 203401) induced pulmonary fibrosis in mice.